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Modeling DNA with Legos

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Modeling DNA with Legos

Students learn best when they develop mental models. For many students this is almost automatic – they see diagrams and can internally translate them into… TBA

But for many other students … TBA

One great solution is to physically create models of molecules… TBA

Strengths and limitations of using Legos TBA

(article to be written)

Legos DNA purines pyrimidines 1

In this next image we see (TBA)

Legos DNA purines pyrimidines 4


Learning Expectations

2016 Massachusetts Science and Technology/Engineering Curriculum Framework

8.MS-PS1-1. Develop a model to describe that (a) atoms combine in a multitude of ways to produce pure substances which make up all of the living and nonliving things that we encounter.

HS-LS1-1. Construct a model of transcription and translation to explain the roles of DNA and RNA that code for proteins that regulate and carry out essential functions of life.

HS-LS1-6. Construct an explanation based on evidence that organic molecules are primarily composed of six elements, where carbon, hydrogen, and oxygen atoms may combine with nitrogen, sulfur, and phosphorus to form monomers that can further combine to form large carbon-based macromolecules.

College Board Standards for College Success: Science

LSM-PE.5.2.2 Construct a representation of DNA replication, showing how the helical DNA molecule unzips and how nucleotide bases pair with the DNA template to form a duplicate of the DNA molecule.

Benchmarks for Science Literacy, AAAS

The information passed from parents to offspring is coded in DNA molecules, long chains linking just four kinds of smaller molecules, whose precise sequence encodes genetic information. 5B/H3*

Genes are segments of DNA molecules. Inserting, deleting, or substituting segments of DNA molecules can alter genes. An altered gene may be passed on to every cell that develops from it. The resulting features may help, harm, or have little or no effect on the offspring’s success in its environment. 5B/H4*


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