Antarctic mantle plume
Let’s All Calm Down and Make Sense of That Antarctic Mantle Plume
Ryan F. Mandelbaum, Gizmodo, 11/8/2017
Three decades ago, scientists began to study the possibility that there was a plume of hot rock coming up from the mantle, heating parts of Western Antarctica. Back in September, researchers published results of a model showing how such a plume might affect the Antarctic ice sheet. Today, these headlines started to appear:

And my brain felt like it started to leak out of my ears. So we’re going to present to you what actually happened, what we know about the plume, and why you shouldn’t worry about “something monstrous.”
It’s definitely a neat idea from a scientific perspective. “I was interested because my first impression was that it’s surprising,” Hélène Seroussi, scientist at NASA’s Jet Propulsion Laboratory told Gizmodo. “There’s this feature under the ice and we still have ice present there. It was interesting to reconcile these two things that were contradictory in the first place.”
Seroussi and her group then tried to build a model of what would happen if a mantle plume did exist there and see what such a plume’s effects on the ice sheet and heating in the ice might be. This model, aided by observations from a NASA satellite, helped explain the amount of heat such a plume might add. It could even melt several centimeters of ice right above, and explain some of the heat creating Antarctica’s hidden lakes and rivers. The researchers published the model in the Journal of Geophysical Research: Solid Earth.

The plume would have been there for around fifty million years, and the ice sheet would have formed atop it. It likely affected the way ice melted at the end of the last Ice Age. But it’s not really something to worry about. “It’s been there forever, it will remain there for a really long time,” said Seroussi. “We don’t have to worry about it. But at the same time, as the future brings more heat… the ice will probably be warmer in this area than in other places.”
The presence and modeling of such heating is important data to have to understand the future of the Antarctic ice sheet. After all, warm ice flows faster than colder ice, like warm honey flows faster than cold honey.
But no one has actually measured a plume. There’s just a new model to help explain a hypothesis. A research associate from the University of Texas, Duncan Young, explained to Gizmodo that the paper “is a valuable use of the advances in ice sheet modeling” integrating the sensitivity of the ice sheet into it. He points out that there’s more up-to-date-data that can be added, including satellite observations. Seroussi also told Gizmodo that more direct observations could help explain what was happening.
So there you have it, dear readers. I was in the midst of reporting this interesting but maybe not so revolutionary paper about a geophysical model and suddenly a bunch of other people saw the press release, didn’t bother to read the paper, then went insane and decided that scientists made a huge discovery. That’s not what happened. But, uh, the model is cool.
[Journal of Geophysical Research: Solid Earth]
Source: https://gizmodo.com/lets-all-calm-down-and-make-sense-of-that-antarctic-man-1820268978
Questions:
- What are the physical layers of the earth? Make a simple, clear diagram and label it. Earth’s layered structure
- Why is the Earth’s interior hot?
- What is the mantle? arth’s layered structure
- What is mantle convection? mantle convection
- How are popular news articles covering this story?
- Scientists don’t explain this story the same way that the newspapers do: How are scientists explaining this story? (See this blog post)
Learning Standards
2016 Massachusetts Science and Technology/Engineering Curriculum Framework
8.MS-ESS2-1. Use a model to illustrate that energy from Earth’s interior drives convection that cycles Earth’s crust, leading to melting, crystallization, weathering, and deformation
of large rock formations, including generation of ocean sea floor at ridges,
submergence of ocean sea floor at trenches, mountain building, and active volcanic
chains.
HS-ESS2-3. Use a model based on evidence of Earth’s interior to describe the cycling of matter due to the outward flow of energy from Earth’s interior and gravitational movement of denser materials toward the interior.
HS-ESS2-4. Use a model to describe how variations in the flow of energy into and out of Earth’s systems over different time scales result in changes in climate. Analyze and interpret data to explain that long-term changes in Earth’s tilt and orbit result in cycles of
climate change such as Ice Ages.
HS-ESS1-5. Evaluate evidence of the past and current movements of continental and oceanic crust, the theory of plate tectonics, and relative densities of oceanic and continental rocks to explain why continental rocks are generally much older than rocks of the ocean floor.
This website is educational. Materials within it are being used in accord with the Fair Use doctrine, as defined by United States law.
§107. Limitations on Exclusive Rights: Fair Use
Notwithstanding the provisions of section 106, the fair use of a copyrighted work, including such use by reproduction in copies or phone records or by any other means specified by that section, for purposes such as criticism, comment, news reporting, teaching (including multiple copies for classroom use), scholarship, or research, is not an infringement of copyright. In determining whether the use made of a work in any particular case is a fair use, the factors to be considered shall include:
the purpose and character of the use, including whether such use is of a commercial nature or is for nonprofit educational purposes;
the nature of the copyrighted work;
the amount and substantiality of the portion used in relation to the copyrighted work as a whole; and
the effect of the use upon the potential market for or value of the copyrighted work. (added pub. l 94-553, Title I, 101, Oct 19, 1976, 90 Stat 2546)
Teaching protein translation
We’re teaching how DNA gets turned into mRNA, and then hooks up to tRNA with amino acids, and then forms proteins. Very important yet it’s not easy for everyone. It can be challenging for ELL and SPED students. Solution? Make it tactile: Use a large table as a cell, and pieces on the table to represent organelles and molecules.
It took time to find right graphics – but this was critical. It’s good to reinforce that cells contain many organelles, even if we’re only using a few of them in any particular lesson.
I printed them out on heavy stock paper. (I need to laminate it next time, but this was a trial run.) Cut out all the pieces.
The trick is to have many nucleotides, so they can get practice with multiple combinations. Here we have 27 bases, for 9 codons, making an 8 amino acid peptide (plus one STOP codon.)
Here is the PDF file with the graphics (DNA to mRNA to ribosome to tRNA) This is what it looks like on a table top, when students use them.


Learning Standards
2016 Massachusetts Science and Technology/Engineering Curriculum Framework
HS-LS1-1. Construct a model of transcription and translation to explain the roles of DNA and RNA that code for proteins that regulate and carry out essential functions of life.
Michelangelo’s Secret Message in the Sistine Chapel
Michelangelo’s Secret Message in the Sistine Chapel: A Juxtaposition of God and the Human Brain
Scientific American, R. Douglas Fields on May 27, 2010
At the age of 17 he began dissecting corpses from the church graveyard. Between the years 1508 and 1512 he painted the ceiling of the Sistine Chapel in Rome. Michelangelo Buonarroti—known by his first name the world over as the singular artistic genius, sculptor and architect—was also an anatomist, a secret he concealed by destroying almost all of his anatomical sketches and notes. Now, 500 years after he drew them, his hidden anatomical illustrations have been found—painted on the ceiling of the Sistine Chapel, cleverly concealed from the eyes of Pope Julius II and countless religious worshipers, historians, and art lovers for centuries—inside the body of God.

This is the conclusion of Ian Suk and Rafael Tamargo, in their paper in the May 2010 issue of the scientific journal Neurosurgery. Suk and Tamargo are experts in neuroanatomy at the Johns Hopkins University School of Medicine in Baltimore, Maryland.
In 1990, physician Frank Meshberger published a paper in the Journal of the American Medical Association deciphering Michelangelo’s imagery with the stunning recognition that the depiction in God Creating Adam in the central panel on the ceiling was a perfect anatomical illustration of the human brain in cross section. Meshberger speculates that Michelangelo surrounded God with a shroud representing the human brain to suggest that God was endowing Adam not only with life, but also with supreme human intelligence.
Now in another panel The Separation of Light from Darkness, Suk and Tamargo have found more. Leading up the center of God’s chest and forming his throat, the researchers have found a precise depiction of the human spinal cord and brain stem.

Is the ceiling of the Sistine Chapel a 500 year-old puzzle that is only now beginning to be solved? What was Michelangelo saying by construction the voice box of God out of the brain stem of man? Is it a sacrilege or homage?
It took Michelangelo four years to complete the ceiling of the Sistine Chapel. He proceeded from east to west, starting from the entrance of the Chapel to finish above the altar. The last panel he painted depicts God separating light from darkness. This is where the researchers report that Michelangelo hid the human brain stem, eyes and optic nerve of man inside the figure of God directly above the altar.
Art critics and historians have long puzzled over the odd anatomical irregularities in Michelangelo’s depiction of God’s neck in this panel, and by the discordant lighting in the region. The figures in the fresco are illuminated diagonally from the lower left, but God’s neck, highlighted as if in a spotlight, is illuminated straight-on and slightly from the right.

How does one reconcile such clumsiness by the world’s master of human anatomy and skilled portrayer of light with bungling the image of God above the altar? Suk and Tamargo propose that the hideous goiter-disfigured neck of God is not a mistake, but rather a hidden message. They argue that nowhere else in any of the other figures did Michelangelo foul up his anatomically correct rendering of the human neck.
They show that if one superimposes a detail of God’s odd lumpy neck in the Separation of Light and Darkness on a photograph of the human brain as seen from below, the lines of God’s neck trace precisely the features of the human brain [see images at right].
There is something else odd about this picture. A role of fabric extends up the center of God’s robe in a peculiar manner. The clothing is bunched up here as is seen nowhere else, and the fold clashes with what would be the natural drape of fabric over God’s torso. In fact, they observe, it is the human spinal cord, ascending to the brain stem in God’s neck. At God’s waist, the robe twists again in a peculiar crumpled manner, revealing the optic nerves from two eyes, precisely as Leonardo Da Vinci had shown them in his illustration of 1487. Da Vinci and Michelangelo were contemporaries and acquainted with each other’s work.
The mystery is whether these neuroanatomical features are hidden messages or whether the Sistine Chapel a Rorshach tests upon which anyone can extract an image that is meaningful to themselves. The authors of the paper are, after all, neuroanatomists. The neuroanatomy they see on the ceiling may be nothing more than the man on the moon.
But Michelangelo also depicted other anatomical features elsewhere in the ceiling, according to other scholars; notably the kidney, which was familiar to Michelangelo and was of special interest to him as he suffered from kidney stones.
If the hidden figures are intentional, what do they mean? The authors resist speculation, but a great artist does not merely reproduce an object in a work of art, he or she evokes meaning through symbolism. Is Separation of Light from Darkness an artistic comment on the enduring clash between science and religion?
Recall that this was the age when the monk Copernicus was denounced by the Church for theorizing that the Earth revolved around the sun. It was a period of struggle between scientific observation and the authority of the Church, and a time of intense conflict between Protestants and Catholics.
It is no secret that Michelangelo’s relationship with the Catholic Church became strained. The artist was a simple man, but he grew to detest the opulence and corruption of the Church. In two places in the masterpiece, Michelangelo left self portraits—both of them depicting himself in torture. He gave his own face to Saint Bartholomew’s body martyred by being skinned alive, and to the severed head of Holofernes, who was seduced and beheaded by Judith.
Michelangelo was a devout person, but later in life he developed a belief in Spiritualism, for which he was condemned by Pope Paul IV. The fundamental tenet of Spiritualism is that the path to God can be found not exclusively through the Church, but through direct communication with God. Pope Paul IV interpreted Michelangelo’s Last Judgment, painted on the wall of the Sistine Chapel 20 years after completing the ceiling, as defaming the church by suggesting that Jesus and those around him communicated with God directly without need of Church. He suspended Michelangelo’s pension and had fig leaves painted over the nudes in the fresco. According to the artist’s wishes, Michelangelo’s body is not buried on the grounds of the Vatican, but is instead interred in a tomb in Florence.
Perhaps the meaning in the Sistine Chapel is not of God giving intelligence to Adam, but rather that intelligence and observation and the bodily organ that makes them possible lead without the necessity of Church directly to God. The material is rich for speculation and the new findings will doubtlessly spark endless interpretation. We may never know the truth, but in Separation of Light from Darkness, Michelangelo’s masterpiece combines the worlds of art, religion, science, and faith in a provocative and awe inspiring work of art, which may also be a mirror.
Images from “Concealed Neuroanatomy in Michelangelo’s Separation of Light From Darkness in the Sistine Chapel,” by Ian Suk and Rafael J. Tamargo in Neurosurgery, Vol. 66, No. 5, pp. 851-861.
About the author: R. Douglas Fields, Ph.D., is a neuroscientist and an adjunct professor at the University of Maryland, College Park. He is author of Why We Snap, about the neuroscience of sudden aggression, and The Other Brain, about glia. Fields serves on Scientific American Mind’s board of advisers.
Related articles
Separation of Light from Darkness. Article on the painting from Wikipedia.
Origami membrane protein
All cell membranes have proteins embedded in them. Each protein has its own job.
Students often draw the proteins in the cell membrane them like this:

Cell membrane lipid bilayer Regents diagram http://www.hobart.k12.in.us/jkousen/Biology/cell.htm#plcell_dia_ans
With more detail we can see that proteins are three-dimensional machines, with movable parts.

Adding more detail, we can now see molecules going in and out of a cell. The membrane proteins open or close as needed to let certain molecules in, and other ones out.

Here, a student in our class build a three dimensional model of a membrane protein. He made one monomer; and then attached several of them to make a polymer.

Instead of attaching eight monomers in a straight line, he’ll form them into a circle:
This becomes a model of a protein that floats in a cell’s membrane,
It can have two shapes, closed or opened, depending on how it’s folded.
It allows certain molecules in or out of a cell, as needed.







For instructions we may refer to a video from AskABiologist:
Proteins are made of building blocks called amino acids, and have their own special shape. Not only do they look different, but they have different jobs to do inside the cell. Some proteins help move things around in the body, others act like support structures or glue to hold parts of the cell together, and some can help reactions in the cell go faster. The protein we’re making is a channel that sits in the outer cell surface, or membrane, and works like a door that lets certain molecules pass through. Some channels are open all the time while others can be closed depending on signals from the cell or the environment.
Narration by Rebecca Elaine Ryan
Original origami design by Florence Temko
Here’s the video from AskABiologist
Proteins fold into biological machines
Here is a great app that teaches us about protein folding – Protein folding
Individual amino acids have side chains with varying properties of electrical charge. When suspended in water, chains of amino acids can move, bend, and interact with one another along the chain and with the surrounding environment. Forces of electrical attraction and repulsion cause the chain to eventually settle into a conformation that maximizes the molecule’s stability.
Explore the folding of proteins using the free educational simulations and activities below. These scientifically accurate models are great for the classroom, homework assignments, or independent learning. Use them to explore some of the forces involved in the creation of three-dimensional structures in proteins: 1. Where do proteins come from. 2. A closer look at amino acids. 3. The impact of electrical charge. 4. The impact of the surrounding medium.
Protein folding: The Concord Consortium
Learning Standards
Massachusetts Curriculum Frameworks: Biology
8.MS-PS1-1. Develop a model to describe that (a) atoms combine in a multitude of ways to produce pure substances which make up all of the living and nonliving things that we encounter, (b) atoms form molecules and compounds that range in size from two to thousands of atoms, and (c) mixtures are composed of different proportions of pure substances.
HS-LS1-6. Construct an explanation based on evidence that organic molecules are primarily composed of six elements, where carbon, hydrogen, and oxygen atoms may combine with nitrogen, sulfur, and phosphorus to form monomers that can further combine to form large carbon-based macromolecules.
Disciplinary Core Idea Progression Matrix: PS1.A Structure of matter: That matter is composed of atoms and molecules can be used to explain the properties of substances, diversity of materials, how mixtures will interact, states of matter, phase changes, and conservation of matter.
Scientists argue that addiction is not a disease
Addiction is not a disease
A neuroscientist argues that it’s time to change our minds on the roots of substance abuse, Laura Miller, for Salon. 6/27/15
A psychologist and former addict insists that the illness model for addiction is wrong, and dangerously so.
The mystery of addiction — what it is, what causes it and how to end it — threads through most of our lives. Experts estimate that one in 10 Americans is dependent on alcohol and other drugs, and if we concede that behaviors like gambling, overeating and playing video games can be addictive in similar ways, it’s likely that everyone has a relative or friend who’s hooked on some form of fun to a destructive degree. But what exactly is wrong with them? For several decades now, it’s been a commonplace to say that addicts have a disease. However, the very same scientists who once seemed to back up that claim have begun tearing it down.
Once, addictions were viewed as failures of character and morals, and society responded to drunks and junkies with shaming, scolding and calls for more “will power.” This proved spectacularly ineffective, although, truth be told, most addicts do quit without any form of treatment. Nevertheless, many do not, and in the mid-20th century, the recovery movement, centered around the 12-Step method developed by the founders of Alcoholics Anonymous, became a godsend for those unable to quit drinking or drugging on their own. The approach spread to so-called “behavioral addictions,” like gambling or sex, activities that don’t even involve the ingestion of any kind of mind-altering substance.
Much of the potency of AA comes from its acknowledgement that willpower isn’t enough to beat this devil and that blame, rather than whipping the blamed person into shape, is counterproductive. The first Step requires admitting one’s helplessness in the face of addiction….
…. Another factor promoting the disease model is that it has ushered addiction under the aegis of the healthcare industry, whether in the form of an illness whose treatment can be charged to an insurance company or as the focus of profit-making rehab centers.
….The recovery movement and rehab industry (two separate things, although the latter often employs the techniques of the former) have always had their critics, but lately some of the most vocal have been the neuroscientists whose findings once lent them credibility.
One of those neuroscientists is Marc Lewis, a psychologist and former addict himself, also the author of a new book “The Biology of Desire: Why Addiction is Not a Disease.”
Lewis’s argument is actually fairly simple: The disease theory, and the science sometimes used to support it, fail to take into account the plasticity of the human brain. Of course, “the brain changes with addiction,” he writes. “But the way it changes has to do with learning and development — not disease.” All significant and repeated experiences change the brain; adaptability and habit are the brain’s secret weapons. The changes wrought by addiction are not, however, permanent, and while they are dangerous, they’re not abnormal.
Through a combination of a difficult emotional history, bad luck and the ordinary operations of the brain itself, an addict is someone whose brain has been transformed, but also someone who can be pushed further along the road toward healthy development. (Lewis doesn’t like the term “recovery” because it implies a return to the addict’s state before the addiction took hold.)
“The Biology of Desire” is grouped around several case studies, each one illustrating a unique path to dependency. A striving Australian entrepreneur becomes caught up in the “clarity, power and potential” he feels after smoking meth, along with his ability to work long hours while on the drug. A social worker who behaves selflessly in her job and marriage constructs a defiant, selfish, secret life around stealing and swallowing prescription opiates. A shy Irishman who started drinking as a way to relax in social situations slowly comes to see social situations as an occasion to drink and then drinking as a reason to hole up in his apartment for days on end.
Each of these people, Lewis argues, had a particular “emotional wound” the substance helped them handle, but once they started using it, the habit itself eventually became self-perpetuating and in most cases ultimately served to deepen the wound.
Each case study focuses on a different part of the brain involved in addiction and illustrates how the function of each part — desire, emotion, impulse, automatic behavior — becomes shackled to a single goal: consuming the addictive substance. The brain is built to learn and change, Lewis points out, but it’s also built to form pathways for repetitive behavior, everything from brushing your teeth to stomping on the brake pedal, so that you don’t have to think about everything you do consciously. The brain is self-organizing. Those are all good properties, but addiction shanghais them for a bad cause.
As Lewis sees it, addiction really is habit; we just don’t appreciate how deeply habit can be engraved on the brain itself. “Repeated (motivating) experience” — i.e., the sensation of having one’s worries wafted away by the bliss of heroin — “produce brain changes that define future experiences… So getting drunk a lot will sculpt the synapses that determine future drinking patterns.”
More and more experiences and activities get looped into the addiction experience and trigger cravings and expectations like the bells that made Pavlov’s dogs salivate, from the walk home past a favorite bar to the rituals of shooting up. The world becomes a host of signs all pointing you in the same direction and activating powerful unconscious urges to follow them. At a certain point, the addictive behavior becomes compulsive, seemingly as irresistibly automatic as a reflex. You may not even want the drug anymore, but you’ve forgotten how to do anything else besides seek it out and take it.
Yet all of the addicts Lewis interviewed for “The Biology of Desire” are sober now, some through tried-and-true 12-Step programs, others through self-designed regimens, like the heroin addict who taught herself how to meditate in prison. Perhaps it’s no surprise that a psychologist would argue for some form of talk therapy addressing the underlying emotional motivations for turning to drugs. But Lewis is far from the only expert to voice this opinion, or to recommend cognitive behavioral therapy as a way to reshape the brain and redirect its systems into less self-destructive patterns.
Without a doubt, AA and similar programs have helped a lot of people. But they’ve also failed others. One size does not fit all, and there’s a growing body of evidence that empowering addicts, rather than insisting that they embrace their powerlessness and the impossibility of ever fully shedding their addiction, can be a road to health as well.
If addiction is a form of learning gone tragically wrong, it is also possible that it can be unlearned, that the brain’s native changeability can be set back on track. “Addicts aren’t diseased,” Lewis writes, “and they don’t need medical intervention in order to change their lives. What they need is sensitive, intelligent social scaffolding to hold the pieces of their imagined future in place — while they reach toward it.”
Further reading
The Irrationality of Alcoholics Anonymous
Its faith-based 12-step program dominates treatment in the United States. But researchers have debunked central tenets of AA doctrine and found dozens of other treatments more effective. By Gabrielle Glaser, The Atlantic 4/2015 The Irrationality of Alcoholics Anonymous, The Atlantic
The Surprising Failures of 12 Steps
How a pseudoscientific, religious organization birthed the most trusted method of addiction treatment. By Jake Flanagan 3/25/2014
https://www.theatlantic.com/health/archive/2014/03/the-surprising-failures-of-12-steps/284616/
Why the Disease Definition of Addiction Does Far More Harm Than Good.
Among other problems, it has obstructed other channels of investigation, including the social, psychological and societal roots of addiction. By Marc Lewis on February 9, 2018
…Viewing addiction as pathology has other, more direct detriments. If you feel that your addiction results from an underlying pathology, as implied by the brain disease model, and if that pathology is chronic, as highlighted by both NIDA and the 12-step movement, then you are less likely to believe that you will ever be free of it or that recovery can result from your own efforts. This characterization of addiction flies in the face of research indicating that a great majority of those addicted to any substance or behavior do in fact recover, and most of those who recover do so without professional care.
Why the Disease Definition of Addiction Does Far More Harm Than Good. Scientific American.
Addiction and the Brain: Development, Not Disease
By Mark Lewis, Neuroethics, April 2017, Volume 10, Issue 1, pp 7–18
I review the brain disease model of addiction promoted by medical, scientific, and clinical authorities in the US and elsewhere. I then show that the disease model is flawed because brain changes in addiction are similar to those generally observed when recurrent, highly motivated goal seeking results in the development of deep habits, Pavlovian learning, and prefrontal disengagement. This analysis relies on concepts of self-organization, neuroplasticity, personality development, and delay discounting. It also highlights neural and behavioral parallels between substance addictions, behavioral addictions, normative compulsive behaviors, and falling in love. I note that the short duration of addictive rewards leads to negative emotions that accelerate the learning cycle, but cortical reconfiguration in recovery should also inform our understanding of addiction. I end by showing that the ethos of the disease model makes it difficult to reconcile with a developmental-learning orientation.
Addiction and the Brain: Development, Not Disease. Neuroethics (journal)
The chronic disease concept of addiction: Helpful or harmful?
Thomas K. Wiens & Lawrence J. Walker. Addiction Research & Theory, Volume 23, 2015 – Issue 4
This study provides empirical support to the notion that framing addiction within a biological conceptualisation, as opposed to a psychological and social framework, weakens perceptions of agency in relation to drinking. Likewise, no evidence was found to support the common assertion that the disease model reduces feelings of stigma and shame.
The chronic disease concept of addiction: Helpful or harmful?
Probability and predictors of remission from lifetime nicotine, alcohol, cannabis, or cocaine dependence
Results from the National Epidemiologic Survey on Alcohol and Related Conditions
By Catalina Lopez-Quintero, M.D., M.P.H., Deborah S. Hasin, Ph.D., […], and Carlos Blanco, M.D., Ph.D. Addiction. 2011 Mar; 106(3): 657–669.
Most People With Addiction Simply Grow Out of It: Why Is This Widely Denied?
By Maia Szalavitz, Addictionblog.org 6/22/2015
The idea that addiction is typically a chronic, progressive disease that requires treatment is false, the evidence shows. Yet the “aging out” experience of the majority is ignored by treatment providers and journalists.
Most People With Addiction Simply Grow Out of It: Why Is This Widely Denied?
Most of Us Still Don’t Get It: Addiction Is a Learning Disorder
By Maia Szalavitz
Addiction is not about our brains being “hijacked” by drugs or experiences—it’s about learned patterns of behavior. Our inability to understand this leads to no end of absurdities.
Most of Us Still Don’t Get It: Addiction Is a Learning Disorder
5 Addiction Myths. A book review of Unbroken Brain: A Revolutionary New Way of Understanding Addiction. Laurel Sindewald, Handshake Media, 6/20/2016
Learned behavior model also explains wide array human behaviors, including political anger
Author David Brin writes
“For years I’ve followed advances that investigate reinforcement processes in the human brain, especially those involving dopamine and other messenger chemicals that are active in mediating pleasure response. One might call this topic chemically-mediated states of arousal that self-reinforce patterns of behavior.
Of course, what this boils down to — at one level — is addiction. But not only in the sense of illegal drug abuse. In very general terms, “addiction” may include desirable things, like bonding with our children and “getting high on life.” These good patterns share with drug addiction the property of being reinforced by repeated chemical stimulus, inside the brain…
Consider studies of gambling. Researchers led by Dr. Hans Breiter of Massachusetts General Hospital examined with functional magnetic resonance imaging (fMRI) which brain regions activate when volunteers won games of chance — regions that overlapped with those responding to cocaine!…
Moving along the spectrum toward activity that we consider more “normal” — neuroscientists at Harvard have found a striking similarity between the brain-states of people trying to predict financial rewards (e.g., via the stock market) and the brains of cocaine and morphine users.
… researchers at Emory University monitored brain activity while asking staunch party members, from both left and right, to evaluate information that threatened their preferred candidate prior to the 2004 Presidential election. “We did not see any increased activation of the parts of the brain normally engaged during reasoning,” said Drew Westen, Emory’s director of clinical psychology. “Instead, a network of emotion circuits lit up… reaching biased conclusions by ignoring information that could not rationally be discounted. Significantly, activity spiked in circuits involved in reward, similar to what addicts experience when they get a fix,” Westen explained.
Addicted to Self-Righteousness? An Open Letter to Researchers In the Fields of Addiction, Brain Chemistry, and Social Psychology
Indignation, addiction and hope — does it help to be “mad as hell?”: David Brin at TEDxUCSD
Fair use
This website is educational. Materials within it are being used in accord with the Fair Use doctrine, as defined by United States law.
§107. Limitations on Exclusive Rights: Fair Use
Notwithstanding the provisions of section 106, the fair use of a copyrighted work, including such use by reproduction in copies or phone records or by any other means specified by that section, for purposes such as criticism, comment, news reporting, teaching (including multiple copies for classroom use), scholarship, or research, is not an infringement of copyright. In determining whether the use made of a work in any particular case is a fair use, the factors to be considered shall include: the purpose and character of the use, including whether such use is of a commercial nature or is for nonprofit educational purposes; the nature of the copyrighted work; the amount and substantiality of the portion used in relation to the copyrighted work as a whole; and the effect of the use upon the potential market for or value of the copyrighted work. (added pub. l 94-553, Title I, 101, Oct 19, 1976, 90 Stat 2546)
Newfound Wormhole Allows Info to Escape Black Holes
By Natalie Wolchover, Senior Writer, Quanta Magazine
October 23, 2017
In 1985, when Carl Sagan was writing the novel Contact, he needed to quickly transport his protagonist Dr. Ellie Arroway from Earth to the star Vega. He had her enter a black hole and exit light-years away, but he didn’t know if this made any sense. The Cornell University astrophysicist and television star consulted his friend Kip Thorne, a black hole expert at the California Institute of Technology (who won a Nobel Prize earlier this month). Thorne knew that Arroway couldn’t get to Vega via a black hole, which is thought to trap and destroy anything that falls in. But it occurred to him that she might make use of another kind of hole consistent with Albert Einstein’s general theory of relativity: a tunnel or “wormhole” connecting distant locations in space-time.
While the simplest theoretical wormholes immediately collapse and disappear before anything can get through, Thorne wondered whether it might be possible for an “infinitely advanced” sci-fi civilization to stabilize a wormhole long enough for something or someone to traverse it.
He figured out that such a civilization could in fact line the throat of a wormhole with “exotic material” that counteracts its tendency to collapse. The material would possess negative energy, which would deflect radiation and repulse space-time apart from itself. Sagan used the trick in Contact, attributing the invention of the exotic material to an earlier, lost civilization to avoid getting into particulars. Meanwhile, those particulars enthralled Thorne, his students and many other physicists, who spent years exploring traversable wormholes and their theoretical implications. They discovered that these wormholes can serve as time machines, invoking time-travel paradoxes — evidence that exotic material is forbidden in nature.
Now, decades later, a new species of traversable wormhole has emerged, free of exotic material and full of potential for helping physicists resolve a baffling paradox about black holes. This paradox is the very problem that plagued the early draft of Contact and led Thorne to contemplate traversable wormholes in the first place; namely, that things that fall into black holes seem to vanish without a trace. This total erasure of information breaks the rules of quantum mechanics, and it so puzzles experts that in recent years, some have argued that black hole interiors don’t really exist — that space and time strangely end at their horizons.
The flurry of findings started last year with a paper that reported the first traversable wormhole that doesn’t require the insertion of exotic material to stay open. Instead, according to Ping Gao and Daniel Jafferis of Harvard University and Aron Wall of Stanford University, the repulsive negative energy in the wormhole’s throat can be generated from the outside by a special quantum connection between the pair of black holes that form the wormhole’s two mouths. When the black holes are connected in the right way, something tossed into one will shimmy along the wormhole and, following certain events in the outside universe, exit the second.
Remarkably, Gao, Jafferis and Wall noticed that their scenario is mathematically equivalent to a process called quantum teleportation, which is key to quantum cryptography and can be demonstrated in laboratory experiments.
John Preskill, a black hole and quantum gravity expert at Caltech, says the new traversable wormhole comes as a surprise, with implications for the black hole information paradox and black hole interiors. “What I really like,” he said, “is that an observer can enter the black hole and then escape to tell about what she saw.” This suggests that black hole interiors really exist, he explained, and that what goes in must come out.

The new wormhole work began in 2013, when Jafferis attended an intriguing talk at the Strings conference in South Korea. The speaker, Juan Maldacena, a professor of physics at the Institute for Advanced Study in Princeton, New Jersey, had recently concluded, based on various hints and arguments, that “ER = EPR.” That is, wormholes between distant points in space-time, the simplest of which are called Einstein-Rosen or “ER” bridges, are equivalent (albeit in some ill-defined way) to entangled quantum particles, also known as Einstein-Podolsky-Rosen or “EPR” pairs. The ER = EPR conjecture, posed by Maldacena and Leonard Susskind of Stanford, was an attempt to solve the modern incarnation of the infamous black hole information paradox by tying space-time geometry, governed by general relativity, to the instantaneous quantum connections between far-apart particles that Einstein called “spooky action at a distance.”
The paradox has loomed since 1974, when the British physicist Stephen Hawking determined that black holes evaporate — slowly giving off heat in the form of particles now known as “Hawking radiation.” Hawking calculated that this heat is completely random; it contains no information about the black hole’s contents. As the black hole blinks out of existence, so does the universe’s record of everything that went inside. This violates a principle called “unitarity,” the backbone of quantum theory, which holds that as particles interact, information about them is never lost, only scrambled, so that if you reversed the arrow of time in the universe’s quantum evolution, you’d see things unscramble into an exact re-creation of the past.
Almost everyone believes in unitarity, which means information must escape black holes — but how? In the last five years, some theorists, most notably Joseph Polchinski of the University of California, Santa Barbara, have argued that black holes are empty shells with no interiors at all — that Ellie Arroway, upon hitting a black hole’s event horizon, would fizzle on a “firewall” and radiate out again.
Many theorists believe in black hole interiors (and gentler transitions across their horizons), but in order to understand them, they must discover the fate of information that falls inside. This is critical to building a working quantum theory of gravity, the long-sought union of the quantum and space-time descriptions of nature that comes into sharpest relief in black hole interiors, where extreme gravity acts on a quantum scale.
The quantum gravity connection is what drew Maldacena, and later Jafferis, to the ER = EPR idea, and to wormholes. The implied relationship between tunnels in space-time and quantum entanglement posed by ER = EPR resonated with a popular recent belief that space is essentially stitched into existence by quantum entanglement. It seemed that wormholes had a role to play in stitching together space-time and in letting black hole information worm its way out of black holes — but how might this work? When Jafferis heard Maldacena talk about his cryptic equation and the evidence for it, he was aware that a standard ER wormhole is unstable and non-traversable. But he wondered what Maldacena’s duality would mean for a traversable wormhole like the ones Thorne and others played around with decades ago. Three years after the South Korea talk, Jafferis and his collaborators Gao and Wall presented their answer. The work extends the ER = EPR idea by equating, not a standard wormhole and a pair of entangled particles, but a traversable wormhole and quantum teleportation: a protocol discovered in 1993 that allows a quantum system to disappear and reappear unscathed somewhere else.
When Maldacena read Gao, Jafferis and Wall’s paper, “I viewed it as a really nice idea, one of these ideas that after someone tells you, it’s obvious,” he said. Maldacena and two collaborators, Douglas Stanford and Zhenbin Yang, immediately began exploring the new wormhole’s ramifications for the black hole information paradox; their paper appeared in April. Susskind and Ying Zhao of Stanford followed this with a paper about wormhole teleportation in July. The wormhole “gives an interesting geometric picture for how teleportation happens,” Maldacena said. “The message actually goes through the wormhole.”
In their paper, “Diving Into Traversable Wormholes,” published in Fortschritte der Physik, Maldacena, Stanford and Yang consider a wormhole of the new kind that connects two black holes: a parent black hole and a daughter one formed from half of the Hawking radiation given off by the parent as it evaporates. The two systems are as entangled as they can be. Here, the fate of the older black hole’s information is clear: It worms its way out of the daughter black hole.
During an interview this month in his tranquil office at the IAS, Maldacena, a reserved Argentinian-American with a track record of influential insights, described his radical musings. On the right side of a chalk-dusty blackboard, Maldacena drew a faint picture of two black holes connected by the new traversable wormhole.
On the left, he sketched a quantum teleportation experiment, performed by the famous fictional experimenters Alice and Bob, who are in possession of entangled quantum particles a and b, respectively.
Say Alice wants to teleport a qubit q to Bob. She prepares a combined state of q and a, measures that combined state (reducing it to a pair of classical bits, 1 or 0), and sends the result of this measurement to Bob. He can then use this as a key for operating on b in a way that re-creates the state q. Voila, a unit of quantum information has teleported from one place to the other.
Maldacena turned to the right side of the blackboard. “You can do operations with a pair of black holes that are morally equivalent to what I discussed [about quantum teleportation]. And in that picture, this message really goes through the wormhole.”
Say Alice throws qubit q into black hole A. She then measures a particle of its Hawking radiation, a, and transmits the result of the measurement through the external universe to Bob, who can use this knowledge to operate on b, a Hawking particle coming out of black hole B. Bob’s operation reconstructs q, which appears to pop out of B, a perfect match for the particle that fell into A. This is why some physicists are excited: Gao, Jafferis and Wall’s wormhole allows information to be recovered from black holes. In their paper, they set up their wormhole in a negatively curved space-time geometry that often serves as a useful, if unrealistic, playground for quantum gravity theorists. However, their wormhole idea seems to extend to the real world as long as two black holes are coupled in the right way: “They have to be causally connected and then the nature of the interaction that we took is the simplest thing you can imagine,” Jafferis explained. If you allow the Hawking radiation from one of the black holes to fall into the other, the two black holes become entangled, and the quantum information that falls into one can exit the other.
The quantum-teleportation format precludes using these traversable wormholes as time machines. Anything that goes through the wormhole has to wait for Alice’s message to travel to Bob in the outside universe before it can exit Bob’s black hole, so the wormhole doesn’t offer any superluminal boost that could be exploited for time travel. It seems traversable wormholes might be permitted in nature as long as they offer no speed advantage. “Traversable wormholes are like getting a bank loan,” Gao, Jafferis and Wall wrote in their paper: “You can only get one if you are rich enough not to need it.”
A Naive Octopus
While traversable wormholes won’t revolutionize space travel, according to Preskill the new wormhole discovery provides “a promising resolution” to the black hole firewall question by suggesting that there is no firewall at black hole horizons. Preskill said the discovery rescues “what we call ‘black hole complementarity,’ which means that the interior and exterior of the black hole are not really two different systems but rather two very different, complementary ways of looking at the same system.” If complementarity holds, as is widely assumed, then in passing across a black hole horizon from one realm to the other, Contact’s Ellie Arroway wouldn’t notice anything strange. This seems more likely if, under certain conditions, she could even slide all the way through a Gao-Jafferis-Wall wormhole.
The wormhole also safeguards unitarity — the principle that information is never lost — at least for the entangled black holes being studied. Whatever falls into one black hole eventually exits the other as Hawking radiation, Preskill said, which “can be thought of as in some sense a very scrambled copy of the black hole interior.”
Taking the findings to their logical conclusion, Preskill thinks it ought to be possible (at least for an infinitely advanced civilization) to influence the interior of one of these black holes by manipulating its radiation. This “sounds crazy,” he wrote in an email, but it “might make sense if we can think of the radiation, which is entangled with the black hole — EPR — as being connected to the black hole interior by wormholes — ER. Then tickling the radiation can send a message which can be read from inside the black hole!” He added, “We still have a ways to go, though, before we can flesh out this picture in more detail.”
Indeed, obstacles remain in the quest to generalize the new wormhole findings to a statement about the fate of all quantum information, or the meaning of ER = EPR.

“Figure 13: Sketch of the entanglement pattern between the black hole and the Hawking radiation. We expect that this entanglement leads to the interior geometry of the black hole.” – Maldacena and Susskind
In Maldacena and Susskind’s paper proposing ER = EPR, they included a sketch that’s become known as the “octopus”: a black hole with tentacle-like wormholes leading to distant Hawking particles that have evaporated out of it.
The authors explained that the sketch illustrates “the entanglement pattern between the black hole and the Hawking radiation. We expect that this entanglement leads to the interior geometry of the black hole.”
But according to Matt Visser, a mathematician and general-relativity expert at Victoria University of Wellington in New Zealand who has studied wormholes since the 1990s, the most literal reading of the octopus picture doesn’t work. The throats of wormholes formed from single Hawking particles would be so thin that qubits could never fit through. “A traversable wormhole throat is ‘transparent’ only to wave packets with size smaller than the throat radius,” Visser explained. “Big wave packets will simply bounce off any small wormhole throat without crossing to the other side.”
Stanford, who co-wrote the recent paper with Maldacena and Yang, acknowledged that this is a problem with the simplest interpretation of the ER = EPR idea, in which each particle of Hawking radiation has its own tentacle-like wormhole.
However, a more speculative interpretation of ER = EPR that he and others have in mind does not suffer from this failing. “The idea is that in order to recover the information from the Hawking radiation using this traversable wormhole,” Stanford said, one has to “gather the Hawking radiation together and act on it in a complicated way.”
This complicated collective measurement reveals information about the particles that fell in; it has the effect, he said, of “creating a large, traversable wormhole out of the small and unhelpful octopus tentacles. The information would then propagate through this large wormhole.” Maldacena added that, simply put, the theory of quantum gravity might have a new, generalized notion of geometry for which ER equals EPR. “We think quantum gravity should obey this principle,” he said. “We view it more as a guide to the theory.”
In his 1994 popular science book, Black Holes and Time Warps, Kip Thorne celebrated the style of reasoning involved in wormhole research. “No type of thought experiment pushes the laws of physics harder than the type triggered by Carl Sagan’s phone call to me,” he wrote; “thought experiments that ask, ‘What things do the laws of physics permit an infinitely advanced civilization to do, and what things do the laws forbid?’”
Newfound Wormhole Allows Information to Escape Black Holes 10
Arxiv paper: Cool horizons for entangled black holes Juan Maldacena and Leonard Susskind
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Teaching about evolution
So, we’re supposed to teach our students about evolution – but where to start? What topics to cover? And in what order should we cover them? And for each topic, what are the relevant learning standards? This sequence works for me:
Abiogenesis & spontaneous generation
Abiogenesis – modern discoveries
Charles Darwin’s Voyage of Discovery and Darwin’s notebook
Fossils: Evidence of evolution over time and Dating of fossils
Convergent evolution and Homologous and analogous structures
clades rotate = equivalent phylogenies
Gradualism vs. Punctuated Equilibrium
Examples of evolution
Where did the idea of evolution develop? How has the idea of evolution changed over time?
Advanced topics
Evolution of the first animals
Ontogeny and Phylogeny: Addressing misconceptions
Horizontal Gene Transfer and Kleptoplasty
Teaching about cells
So, we’re supposed to teach our students biology – but where to start? What topics to cover? And in what order should we cover them? And for each topic, what are the relevant learning standards? This sequence works for me:
Characteristics of Life
Organelles, an introduction
Organelles: In more depth
What is the role of enzymes in cells?
Then we move on to types of cells
Now the nitty-gritty: Cell reproduction
For those teaching Honors Biology
Active transport across cell membranes
Psychopathy
Psychopathy, sometimes considered synonymous with sociopathy, is a personality disorder characterized by persistent antisocial behavior, impaired empathy and remorse, and bold, disinhibited, egotistical traits.
The Diagnostic and Statistical Manual of Mental Disorders (DSM) and International Classification of Diseases (ICD) introduced the diagnoses of antisocial personality disorder (ASPD) and dissocial personality disorder respectively, stating that these diagnoses have been referred to as psychopathy or sociopathy. (Antisocial personality disorder)

Venn diagram displays the overlap between general Personality Disorder (PD), Antisocial Personality Disorder (ASPD), and Psychopathy for the sample in Baliousis et al. (2019)
Image above from What Makes a Criminal a Psychopath
Psychopathy has been proposed as a specifier under an alternative model for ASPD. In the DSM-5, under “Alternative DSM-5 Model for Personality Disorders”, ASPD with psychopathic features is described as characterized by “a lack of anxiety or fear and by a bold interpersonal style that may mask maladaptive behaviors (e.g., fraudulence).” Low levels of withdrawal and high levels of attention-seeking combined with low anxiety are associated with “social potency” and “stress immunity” in psychopathy.
Theodore Millon suggested 5 subtypes of ASPD.
Subtype |
Features |
|---|---|
Nomadic antisocial (including schizoid and avoidant features) |
Drifters; roamers, vagrants; adventurer, itinerant vagabonds, tramps, wanderers; they typically easy to adapt in difficult situations, shrewd and impulsive. Mood centers in doom and invincibility. |
Malevolent antisocial (including sadistic and paranoid features) |
Belligerent, mordant, rancorous, vicious, sadistic, malignant, brutal, resentful; anticipates betrayal and punishment; desires revenge; truculent, callous, fearless; guiltless; many dangerous criminal fits this criteria. |
Covetous antisocial (including negativistic features) |
Rapacious, begrudging, discontentedly yearning; an angle was seen as assertively hostile as to dominate; was envious, seek more profit, and avariciously greedy; pleasures more in taking than in having. |
Risk-taking antisocial(including histrionic features) |
Dauntless, venturesome, intrepid, bold, audacious, daring; reckless, foolhardy, heedless; unfazed by hazard; pursues perilous ventures. |
Reputation-defending antisocial (including narcissisticfeatures) |
Needs to be thought of as infallible, unbreakable, indomitable, formidable, inviolable; intransigent when status is questioned; overreactive to slights. |
The study of psychopathy is an active field of research.
Unfortunately the term is used by the general public, popular press, and in fictional portrayals in a variety of contradictory and non-scientific ways, and occasionally as an ad homenim remark.
Conduct disorder
A prolonged pattern of antisocial behavior in childhood and/or adolescence, and may be seen as a precursor to Antisocial personality disorder (ASPD), also known as sociopathy. The DSM allows differentiating between childhood onset before age 10, and adolescent onset at age 10 and later. Childhood onset is argued to be more due to a personality disorder caused by neurological deficits interacting with an adverse environment.
The DSM-5 includes a specifier for those with conduct disorder who also display a callous, unemotional interpersonal style across multiple settings and relationships. The specifier is based on research which suggests that those with conduct disorder who also meet criteria for the specifier tend to have a more severe form of the disorder with an earlier onset as well as a different response to treatment. – Wikipedia
Is Conduct disorder compulsory in Psychopathy?
Cherie Valeithian, I am a licensed psychologist. In a word, yes, at least when using The Diagnostic and Statistical Manual of Mental and Emotional Disorders, published by the American Psychiatric Association, and currently in it’s 5th edition. The official name for psychopathy/sociopathy is Antisocial Personality Disorder, which is diagnosed only in individuals age 18 or older. One of the criteria required for that diagnosis is that the person met criteria for Conduct Disorder prior to the age of 18, whether or not the person was ever officially diagnosed as such….
https://www.quora.com/Is-Conduct-disorder-compulsory-in-Psychopathy
Hare Psychopathy Checklist
The Hare PCL-R contains two parts, a semi-structured interview and a review of the subject’s file records and history. During the evaluation, the clinician scores 20 items that measure central elements of the psychopathic character. The items cover the nature of the subject’s interpersonal relationships; his or her affective or emotional involvement; responses to other people and to situations; evidence of social deviance; and lifestyle.
The material thus covers two key aspects that help define the psychopath: selfish and unfeeling victimization of other people, and an unstable and antisocial lifestyle.
The twenty traits assessed by the PCL-R score are:
-
glib and superficial charm
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grandiose (exaggeratedly high) estimation of self
-
need for stimulation
-
pathological lying
-
cunning and manipulativeness
-
lack of remorse or guilt
-
shallow affect (superficial emotional responsiveness)
-
callousness and lack of empathy
-
parasitic lifestyle
-
poor behavioral controls
-
sexual promiscuity
-
early behavior problems
-
lack of realistic long-term goals
-
impulsivity
-
irresponsibility
-
failure to accept responsibility for own actions
-
many short-term marital relationships
-
juvenile delinquency
-
revocation of conditional release
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criminal versatility
The interview portion of the evaluation covers the subject’s background, including such items as work and educational history; marital and family status; and criminal background. Because psychopaths lie frequently and easily, the information they provide must be confirmed by a review of the documents in the subject’s case history.
Results
When properly completed by a qualified professional, the PCL-R provides a total score that indicates how closely the test subject matches the “perfect” score that a classic or prototypical psychopath would rate. Each of the twenty items is given a score of 0, 1, or 2 based on how well it applies to the subject being tested.
A prototypical psychopath would receive a maximum score of 40. One with absolutely no psychopathic traits would receive a score of zero. A score of 30 or above qualifies a person for a diagnosis of psychopathy. People with no criminal backgrounds normally score around 5. Many non-psychopathic criminal offenders score around 22.
Psychiatry
Psychiatry is a medical field devoted to the diagnosis, study, and treatment of mental disorders.
The following intro has been adapted from Wikipedia:

Psychiatric assessment of a person typically begins with a case history and mental status examination.
Physical examinations and psychological tests may be conducted.
On occasion, neuroimaging or other neurophysiological techniques are used.
Mental disorders are often diagnosed in accordance with criteria listed in diagnostic manuals. Examples include:
Diagnostic and Statistical Manual of Mental Disorders (DSM),
by the American Psychiatric Association (APA),
and the International Classification of Diseases (ICD),
by the World Health Organization (WHO).
Psychopharmacology became important starting with Otto Loewi‘s discovery of the neuromodulatory properties of acetylcholine. This is the first-known neurotransmitter.
Neuroimaging was first utilized as a tool for psychiatry in the 1980s.

The discovery of chlorpromazine‘s effectiveness in treating schizophrenia in 1952 revolutionized treatment of the disorder.
Another major discovery (1948) was the chemical lithium carbonate. This molecule can stabilize mood highs and lows in bipolar disorder.
Biopsychiatric research – This has shown us how biology is related to psychiatry.
We have discovered that there are relationships between certain mental illnesses, and certain abnormalities of brain structure. This includes schizophrenia.
We have also discovered that some genetic mutations are related to psychiatric disorders. This includes schizophrenia, bipolar disorder, and autism.
In general, though, science has not progressed to the stage that we can identify clear biomarkers of these disorders.
In other words, we don’t have specific biochemical tests for mental disorders.
Mental disorders don’t exist on their own
From The hidden links between mental disorders
Psychiatrists have a dizzying array of diagnoses and not enough treatments.
Hunting for the hidden biology underlying mental disorders could help.
Michael Marshall, Nature 581, 19-21 (2020). doi: 10.1038/d41586-020-00922-8
In 2018, psychiatrist Oleguer Plana-Ripoll was wrestling with a puzzling fact about mental disorders. He knew that many individuals have multiple conditions — anxiety and depression, say, or schizophrenia and bipolar disorder. He wanted to know how common it was to have more than one diagnosis, so he got his hands on a database containing the medical details of around 5.9 million Danish citizens.
He was taken aback by what he found. Every single mental disorder predisposed the patient to every other mental disorder — no matter how distinct the symptoms. “We knew that comorbidity was important, but we didn’t expect to find associations for all pairs,” says Plana-Ripoll, who is based at Aarhus University in Denmark.
The study tackles a fundamental question that has bothered researchers for more than a century. What are the roots of mental illness? In the hope of finding an answer, scientists have piled up an enormous amount of data over the past decade, through studies of genes, brain activity and neuroanatomy. They have found evidence that many of the same genes underlie seemingly distinct disorders, such as schizophrenia and autism, and that changes in the brain’s decision-making systems could be involved in many conditions.
They have a few theories. Perhaps there are several dimensions of mental illness — so, depending on how a person scores on each dimension, they might be more prone to some disorders than to others. An alternative, more radical idea is that there is a single factor that makes people prone to mental illness in general: which disorder they develop is then determined by other factors. Both ideas are being taken seriously, although the concept of multiple dimensions is more widely accepted by researchers.
The details are still fuzzy, but most psychiatrists agree that one thing is clear: the old system of categorizing mental disorders into neat boxes does not work. They are also hopeful that, in the long run, replacing this framework with one that is grounded in biology will lead to new drugs and treatments. Researchers aim to reveal, for instance, the key genes, brain regions and neurological processes involved in psychopathology, and target them with therapies. Although it might take a while to get there, says Steven Hyman of the Broad Institute of MIT and Harvard in Cambridge, Massachusetts, “I am long-term optimistic if the field really does its work.”
Related articles
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Is a ‘Spectrum’ the Best Way to Talk About Autism?
Learning styles and multiple intelligences
Psychopathy
Psychopaths Don’t Care If They Hurt You. This Is Why. New research shows why the psychopathic are so likely to harm others.
Detecting genetic disorders with 3d face scans
Link between marijuana and pyschosis, and depression, hyperactivity, and inattention in children.
Mysterious link between immune system and mental illness – He Got Schizophrenia. He Got Cancer. And Then He Got Cured.
Article on mental health disorders
NIMH Disruptive Mood Dysregulation Disorder
Learning Standards
Massachusetts Comprehensive Health Curriculum Framework
PreK–12 STANDARD 5: Mental Health. Students will acquire knowledge about emotions and physical health, the management of emotions, personality and character development, and social awareness; and will learn skills to promote self-acceptance, make decisions, and cope with stress, including suicide prevention.
Benchmarks: American Association for the Advancement of Science
Stresses are especially difficult for children to deal with and may have long-lasting effects. 6F/H1
Biological abnormalities, such as brain injuries or chemical imbalances, can cause or increase susceptability to psychological disturbances. 6F/H2
Reactions of other people to an individual’s emotional disturbance may increase its effects. 6F/H3
Human beings differ greatly in how they cope with emotions and may therefore puzzle one another. 6F/H4
Ideas about what constitutes good mental health and proper treatment for abnormal mental states vary from one culture to another and from one time period to another. 6F/H5
Psychological distress may also affect an individual’s vulnerability to biological disease. 6F/H6** (SFAA)
According to some theories of mental disturbance, anger, fear, or depression may result from exceptionally upsetting thoughts or memories that are blocked from becoming conscious. 6F/H7** (SFAA)

